Fatmata joined the Young-Pearse lab in the summer of 2020 as a research technician following graduation from Middlebury College. She works closely with Marty Fernandez on research projects relating to Alzheimer’s disease and Christianson syndrome. She hopes to enter Medical School in Fall 2022.
Courtney is a graduate student in the Biological and Biomedical Sciences program at Harvard Medical School and joined our lab in the summer of 2020. Courtney’s project involves the targeted investigation and functional characterization of genes implicated in neuropsychiatric disease using iPSC models.
Yan Bi is a visiting graduate student from Shanghai Jiao Tong University and joined our lab from Sep. 2019. Her research project focuses upon understanding the function of genes linked to AD and mental illness during human neocortical development.
Renee is a Senior Administrative Assistant who’s been helping the Young-Pearse lab since 2019. She is our point-person for grant submission, scheduling, onboarding of new lab members and other administrative lab business.
Vicky is a Graduate student in the Biological and Biomedical Sciences program at Harvard Medical School and joined our lab in summer of 2017. Vicky’s project involves differentiating iPSCs into induced microglia and co-culturing them with induced neurons and astrocytes to recapitulate the micro-environment to best model neuroimmune interactions between different cell types in disease.
Yi-Chen joined our lab as a postdoctoral fellow in January 2020. She studies accumulation and degradation of hyperphosphorylated Tau in Alzheimer’s disease using iPSC-derived neurons.
Seeley joined the Young-Pearse lab in the summer of 2020 after teaching high school Biology and Neuroscience in Connecticut for two years. She graduated from Skidmore College in 2018, where she majored in Neuroscience and played field hockey. As a Research Technician, her work will involve iPSCs, neurons and mice and will focus on the Blood Brain Barrier as it relates to Alzheimer’s Disease. Outside of the lab, Seeley enjoys spending time with family, traveling, and cooking!
Marty Fernandez PhD
Marty is a postdoctoral fellow specializing in the biochemical mechanisms by which the Amyloid Precursor Protein (APP) is sequentially cleaved into smaller entities that can either be harmless or highly detrimental to the aging human brain.
Hyo is a graduate student in the Program in Neurosciences at Harvard Medical School and has been working on her thesis in our lab since the summer of 2017. Hyo is studying Aβ clearance in sporadic Alzheimer’s disease using iPSC-derived astrocytes.
Richard V. Pearse II PhD
Richard is a Senior Scientist with more than 20 years experience in medical research. He has been with our lab since the spring of 2017 and is primarily responsible for RNAseq library development, data pipeline development, bioinformatics, and consultation.
Lizzy has been a technician in our lab since Summer 2019. She works primarily in iPSCs and neurons and is continuing Julie’s work of developing a functional assay to measure synaptic release through fluorescence. Outside of the TC rooms, Lizzy is managing our mouse colony, developing cell lines to study how genetic sex impacts Alzheimer’s pathology, and using CRISPR-Cas9 technology to generate a tau knockout cell line. She hopes to enter medical school in fall 2021!